In 2014, Annable starred on the Fox series Red Band Society, where he played the role of pediatric oncologist and surgeon Dr. The movie was realsed in theaters on August 4, 2017.
Annable dropped out of college in 2003 to pursue his acting career.
Adam Mc Andrew on the Fox medical drama Red Band Society (2014–15) and Pierce Harrison on the NBC medical drama Heartbeat (2016). He grew up in Walden, a village in New York, where he played baseball, rugby and hockey.
His father is Christian and his mother is Jewish, and he was "raised both".
After leaving SUNY Plattsburgh, Annable studied acting at the Neighborhood Playhouse in New York with Richard Pinter.
In 2002, Annable made his acting debut in an episode of the NBC crime drama Third Watch.